PCR: a question of taste

Using their own DNA, students will discover and compare their version of a bitter taste receptor gene.

Who is it for: Key stage 4 and post-16

Duration: 5 hours (with 30 minute lunch)

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Student using PCR equipment during workshop at Life Science Centre in Newcastle.

Students will explore how different genetic variants evolve in populations and consider a case of convergent evolution.

Using their own DNA students will discover and compare their version of a bitter taste receptor gene (their genotype) to their ability to taste the bitter compound (their phenotype).

In our specially equipped laboratory students will carry out modern molecular biology techniques including; DNA extraction, micropipetting, polymerase chain reaction (PCR), restriction enzyme digest, and gel electrophoresis.

Curriculum links

Key stage 4 and post-16

Biology

Chemistry

AS/A Level Biology and BTEC Applied Science
Biological molecules
DNA, genes and chromosomes
Genetics and evolution
Practical skills in biology

By the end of the workshops students will have discovered:

How we can use molecular biology techniques to identify genotypes.

Whether they are a taster or non-taster of PTC and their underlying genotype which causes this characteristic.

How we can use PCR to make copies of a specific piece of DNA.

How restriction enzymes are used to select the relevant sections of DNA for analysis.

How electrophoresis can be used to analyse DNA samples.

How to carry out key molecular biology techniques using specialist equipment including; micro-pipetting, DNA extraction, restriction enzyme digest, gel electrophoresis and PCR (Polymerase chain reaction).

School trip prices

We allow a ratio of 1 adult to every 5 children for most groups. Additional adults over this ratio will be charged. In the case of SEN groups, we may offer further free adult support on request – please contact us to discuss your requirements.

Teachers and adult helpers go FREE!