Skip to content

Disease outbreak!

Students step into the role of a clinical bacteriologist and investigate DNA samples from new outbreaks of bacterial disease.

Who is it for: Key stage 4 and post-16
Duration: 2.5 hours
Students step into the role of a clinical bacteriologist and investigate DNA sample like this microscopic blue bacteria in this Key Stage 4 schools' workshop.

Explore the ongoing battle between bacterial pathogens and the human immune system and how this leads to evolution, driven by changes in bacterial DNA.

Students step into the role of a clinical bacteriologist and investigate DNA samples from new outbreaks of bacterial disease, comparing them to reference samples. Will the Streptococcus pyogenes bacteria in question cause a mild case of strep throat or a much more deadly episode of necrotising fasciitis?

During the workshop students use research-grade equipment to carry out key lab techniques.

Curriculum links

Key stage 4 and post-16
Biology
  • KS4 Science - Cell Biology, Health, disease and the development of medicines, Evolution, inheritance and variation, working scientifically.
  • AS/A Level Biology - Cells, Biological molecules, Genetics and Evolution
  • OCR AS & Level biology: PAG 6.2 Electrophoresis of DNA fragments for analysis.
  • Edexcel Level 3 Advanced GCE (A level) Biology A: Core practical 14: Use gel electrophoresis to separate DNA fragments of different lengths.

By the end of the workshops students will have discovered:

Life logo icon

That small changes to bacterial DNA can mean significant changes to the symptoms humans experience.

Pathogen icon.

That humans have evolved defences again pathogens.

Enzyme icon.

How restriction enzymes are used to select the relevant sections of DNA for analysis.

Petri dish icon.

How electrophoresis can be used to analyse DNA samples.

Dropper icon

How to carry out key lab techniques including; micro-pipetting, restriction enzyme digests and gel electrophoresis.